1. Li G, Zhao Y, Li K, et al. (2023) Effectiveness and safety of the PD-1 inhibitor Lenvatinib plus radiotherapy in patients with HCC with main PVTT: Real-world data from a tertiary center. J Hepatocell Carcinoma, 10: 2037-2048. [DOI:10.2147/JHC.S432542]

2. Nomura T, Tani J, Deguchi A, et al. (2019) Efficacy of combined modality therapy with sorafenib following hepatic arterial injection chemotherapy and three-dimensional conformal radiotherapy for advanced hepatocellular carcinoma with major vascular invasion. Mol Clin Oncol, 11(5): 447-454. [DOI:10.3892/mco.2019.1920]

3. Shi X, Liu J, Wang G (2023) A peroxidase-like magneto-gold nanozyme AuNC@Fe(3)O(4) with photothermal effect for induced cell apoptosis of hepatocellular carcinoma cells in-vitro. Front Bioeng Biotechnol, 11: 1168750. [DOI:10.3389/fbioe.2023.1168750]

4. Tian Z, Zhao J, Wang Y (2022) The prognostic value of TPM1-4 in hepatocellular carcinoma. Cancer Med, 11(2): 433-446. [DOI:10.1002/cam4.4453]

5. Wang K, Liu Z, Hong P, et al. (2022) T.H.R.O.B.V.S. Score - A Comprehensive Model to Predict the Surgical Complexity of Renal Cell Carcinoma With Tumor Thrombus. Front Oncol, 12: 900550. [DOI:10.3389/fonc.2022.900550]

6. Xi M, Zhang L, Zhao L, et al. (2013) Effectiveness of stereotactic body radiotherapy for hepatocellular carcinoma with portal vein and/or inferior vena cava tumor thrombosis. PLoS One, 8(5): e63864. [DOI:10.1371/journal.pone.0063864]

7. Yildirim, OM, Bingolbali A, Bozkurt A, et al. (2023). Monte Carlo calculations of critical organ doses in radioembolization therapy of primary liver tumors via 90Y microspheres. Int J Radiat Res, 21(3): 353-360. [DOI:10.61186/ijrr.21.3.353]

8. Nakazawa T, Adachi S, Kitano M, et al. (2007) Potential prognostic benefits of radiotherapy as an initial treatment for patients with unresectable advanced hepatocellular carcinoma with invasion to intrahepatic large vessels. Oncology, 73: 90-97. [DOI:10.1159/000120996]

9. Llovet JM, Bustamante J, Castells A, et al. (1999) Natural history of untreated nonsurgical hepatocellular carcinoma: rationale for the design and evaluation of therapeutic trials. Hepatology, 29: 62-67. [DOI:10.1002/hep.510290145]

10. Zhang JJ, Wang ZX, Niu JX, et al. (2021). Successful totally laparoscopic right trihepatectomy following conversion therapy for hepatocellular carcinoma: A case report. World J Clin Cases, 9(22), 6469-6477. [DOI:10.12998/wjcc.v9.i22.6469]

11. Zhou J, Sun H, Wang Z, et al. (2023). Guidelines for the Diagnosis and Treatment of Primary Liver Cancer (2022 Edition). Liver Cancer, 12(5): 405-444.

12. Zeng ZC, Fan J, Tang ZY, et al. (2005) A comparison of treatment combinations with and without radiotherapy for hepatocellular carcinoma with portal vein and／or inferior vena cava tumor thrombus. Int J Radiat Oncol Biol Phys, 61: 432-43. [DOI:10.1016/j.ijrobp.2004.05.025]

13. Zhu XD, Liang SX, Wang AY, et al. (2005) Hypofractionated three dimensional conformal radiotherapy for primary liver cancer with portal vein tumor thrombosis. Chin J Radial Oncol 14: 476-8.

14. Kim JY, Chung SM, Choi BO, Kay CS (2011) Hepatocellular carcinoma with portal vein tumor thrombosis: improved treatment outcomes with external beam radiation therapy. Hepatol Res, 41: 813-24. [DOI:10.1111/j.1872-034X.2011.00826.x]

15. Yoon SM, Lim YS, Won HJ, et al. (2012) Radiotherapy plus transarterial chemoembolization for hepatocellular carcinoma invading the portal vein: long-term patient outcomes. Int J Radiat Oncol Biol Phys, 82: 2004-11. [DOI:10.1016/j.ijrobp.2011.03.019]

16. Koo JE, Kim JH, Lim YS, et al. (2010) Combination of transarterial chemoembolization and three-dimensional conformal radiotherapy for hepatocellular carcinoma with inferior vena cava tumor thrombus. Int J Radiat Oncol Biol Phys, 78: 180-87. [DOI:10.1016/j.ijrobp.2009.07.1730]

17. Rim CH, Yang DS, Park YJ, et al. (2012) Effectiveness of high-dose three-dimensional conformal radiotherapy in hepatocellular carcinoma with portal vein thrombosis. Jpn J Clin Oncol, 42: 721-9. [DOI:10.1093/jjco/hys082]

18. Toya R, Murakami R, Baba Y, et al. (2007) Conformal radiation therapy for portal vein tumor thrombosis of hepatocellular carcinoma. Radiother Oncol, 84: 266-71. [DOI:10.1016/j.radonc.2007.07.005]

19. Ministry of health, People's Republic of China (2011) Guidelines for diagnosis and treatment of primary liver cancer. Chin Clin Oncol, 16: 929-46.

20. Liovet JM, Di Bisceglie AM, Bruix J, et al. (2008) Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst, 100: 698-711. [DOI:10.1093/jnci/djn134]

21. Addario L, Tritto G, Cavaglià E, et al. (2011) Preserved liver function, portal thrombosis and absence of oesophageal varices are risk factors for metastasis of hepatocellular carcinoma. Dig Liver Dis, 43: 319-24. [DOI:10.1016/j.dld.2010.09.003]

22. Tazawa J, Maeda M, Sakai Y, et al. (2001) Radiation therapy in combination with transcatheter arterial chemoembolization for hepatocellular carcinoma with extensive portal vein involvement. J Gastroenterol Hepatol, 16: 660-5. [DOI:10.1046/j.1440-1746.2001.02496.x]

23. Toya R, Murakami R, Baba Y, et al. (2007) Conformal radiation therapy for portal vein tumor thrombosis of hepatocellular carcinoma. Radiother Oncol, 84: 266-71. [DOI:10.1016/j.radonc.2007.07.005]

24. Tse RV, Hawkins M, Lockwood G, et al. (2008) Phase I study of individualized stereotactic body radiotherapy for hepatocellular carcinoma and intrahepatic cholangiocarcinoma. J Clin Oncol, 26: 657-64. [DOI:10.1200/JCO.2007.14.3529]

25. Lee MT, Kim JJ, Dinniwell R, et al. (2009) Phase I study of individualized stereotactic body radiotherapy of liver metastases. J Clin Oncol, 27: 1585-91. [DOI:10.1200/JCO.2008.20.0600]

26. Ando E, Yamashita F, Tanaka M, Tanikawa K (1997) A novel chemotherapy for advanced hepatocellular carcinoma with tumor thrombosis of the main trunk of the portal vein. Cancer, 79: 1890-6. https://doi.org/10.1002/(SICI)1097-0142(19970515)79:10<1890::AID-CNCR8>3.0.CO;2-K [DOI:10.1002/(SICI)1097-0142(19970515)79:103.0.CO;2-K]

27. Huang YJ, Hsu HC, Wang CY, et al. (2009) The treatment responses in cases of radiation therapy to portal vein thrombosis in advanced hepatocellular carcinoma. Int J Radiat Oncol Biol Phys, 73: 1155-63. [DOI:10.1016/j.ijrobp.2008.06.1486]

28. Han KH, Seong J, Kim JK, et al. (2008) Pilot clinical trial of localized concurrent chemoradiation therapy for locally advanced hepatocellular carcinoma with portal vein thrombosis. Cancer, 113: 995-1003. [DOI:10.1002/cncr.23684]

29. Choi BO, Choi IB, Jang HS, et al. (2008) Stereotactic body radiation therapy with or without transarterial chemoembolization for patients with primary hepatocellular carcinoma: preliminary analysis. BMC Cancer, 8: 351. [DOI:10.1186/1471-2407-8-351]

30. Kim JY, Yoo EJ, Jang JW, et al. (2013) Hypofractionated radiotheapy using helical tomotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis. Radiation Oncology, 8: 15. [DOI:10.1186/1748-717X-8-15]

31. Cheng AL, Kang YK, Chen Z, et al. (2009) Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol, 10: 25-34. [DOI:10.1016/S1470-2045(08)70285-7]

32. Llovet JM, Ricci S, Mazzaferro V, et al. (2008) Sorafenib in advanced hepatocellular carcinoma. N Engl J Med, 359: 378-90. [DOI:10.1056/NEJMoa0708857]

33. Choi BO, Choi IB, Jang HS, et al. (2008) Stereotactic body radiation therapy with or without transarterial chemoembolization for patients with primary hepatocellular carcinoma: preliminary analysis. BMC Cancer, 8: 351. [DOI:10.1186/1471-2407-8-351]

34. Nakagawa K, Yamashita H, Shiraishi K, et al. (2005) Radiation therapy for portal venous invasion by hepatocellular carcinoma. World J Gastroenterol, 11: 7237-41. [DOI:10.3748/wjg.v11.i46.7237]

35. Park HC, Seong J, Han KH, et al. (2002) Dose-response relationship in local radiotherapy for hepatocellular carcinoma. Int J Radiat Oncol Biol Phys, 54: 150-55. [DOI:10.1016/S0360-3016(02)02864-X]

36. McIntosh A, Hagspiel KD, Al-Osaimi AM, et al. (2009) Accelerated treatment using intensity modulated radiation therapy plus concurrent capecitabine for unresectable hepatocellular carcinoma. Cancer, 115: 5117-25. [DOI:10.1002/cncr.24552]