[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
IJRR Information::
For Authors::
For Reviewers::
Subscription::
News & Events::
Web Mail::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
ISSN
Hard Copy 2322-3243
Online 2345-4229
..
Online Submission
Now you can send your articles to IJRR office using the article submission system.
..

AWT IMAGE

AWT IMAGE

:: Volume 22, Issue 3 (7-2024) ::
Int J Radiat Res 2024, 22(3): 647-655 Back to browse issues page
Uncovering the mechanisms by which acupuncture improves motor function after stroke through neuroplasticity revealed by magnetic resonance imaging techniques
Y. Wu , J. Li , L. Pei
Department of Acupuncture and Rehabilitation, Jiangsu Province Hospital of Chinese Medicine Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, China , plx821016@163.com
Abstract:   (923 Views)
Background: The motor function defects in stroke patients are mainly caused by damage to brain neurons and network disconnection, as viewed through neuroimaging. Structural and functional magnetic resonance imaging (sMRI and fMRI) are the most commonly used techniques in studying central nervous system diseases. This article reviews recent technological research to provide evidence for acupuncture research and development. Materials and Methods: Relevant articles were obtained from PubMed and China national knowledge infrastructure (CNKI) databases, as well as from CNKI database from 2014 to 2023. The data were then reviewed and the citations were examined. Results: The non-invasive technique of magnetic resonance imaging (MRI) is highly effective in accurately identifying abnormal brain activities, making it a top choice. As MRI technology rapidly evolves, additional techniques such as diffusion kurtosis imaging (DKI), diffusion spectrum imaging (DSI), and neurite orientation dispersion and density imaging (NODDI) can be used to observe post-IS motor neural injuries and related neural reshaping. Conclusions: These techniques about MRI could help doctors better understand the biological mechanisms underlying neural pathways and motor deficits in IS, aiding in the development of targeted therapies.
Keywords: Acupuncture, stroke, motor function impairment, hemiparesis, neuroplasticity, MRI.
Full-Text [PDF 726 kb]   (292 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
References
1. GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors (2021) 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol, 20(10): 795-820.
2. Tu WJ, Zhao Z, Yin P, et al. (2023) Estimated Burden of Stroke in China in 2020. JAMA Netw Open, 6(3): e231455. [DOI:10.1001/jamanetworkopen.2023.1455]
3. Xuefang L, Guihua W, Fengru M (2021) The effect of early cognitive training and rehabilitation for patients with cognitive dysfunction in stroke. Int J Methods Psychiatr Res, 30(3): e1882. [DOI:10.1002/mpr.1882]
4. Frenkel-Toledo S, Levin MF, Berman S, et al. (2022) Shared and distinct voxel-based lesion-symptom mappings for spasticity and impaired movement in the hemiparetic upper limb. Sci Rep, 12(1): 10169. [DOI:10.1038/s41598-022-14359-8]
5. Olafson ER, Jamison KW, Sweeney EM, et al. (2021) Functional connectome reorganization relates to post-stroke motor recovery and structural and functional disconnection. Neuroimage. Neuroimage, 245: 118642. [DOI:10.1016/j.neuroimage.2021.118642]
6. Zheng WR, Li EC, Peng S, et al. (2020) Tu Youyou winning the Nobel Prize: Ethical research on the value and safety of traditional Chinese medicine. Bioethics, 34(2): 166-171. [DOI:10.1111/bioe.12456]
7. Mortara L, Coco G, Pozzi C (2022) Biomedicine and traditional Chinese medicine: a fruitful scientific and cultural interaction. Acta Biomed, 93(1): e2022070. [DOI:10.1155/2022/9093614]
8. Guo X and Cheng B (2022) Clinical Effects of Acupuncture for Stroke Patients Recovery. J Healthc Eng, 2022: 9962421. [DOI:10.1155/2022/9962421]
9. Xu J, Pei J, Fu QH, et al. (2020) Earlier Acupuncture Enhancing Long-Term Effects on Motor Dysfunction in Acute Ischemic Stroke: Retrospective Cohort Study. Am J Chin Med, 48(8): 1787-1802. [DOI:10.1142/S0192415X20500895]
10. Mu JD, Ma LX, Zhang Z, et al. (2023) The factors affecting neurogenesis after stroke and the role of acupuncture. Front Neurol, 14: 1082625. [DOI:10.3389/fneur.2023.1082625]
11. Liao Y, Liu F, Yang J, et al. (2022) Analysis of the Efficacy of Acupuncture Combined with Rehabilitation Training in the Treatment of Upper Limb Spasm after Stroke: A Systematic Review and Meta-Analysis. Biomed Res Int, 2022: 8663356. [DOI:10.1155/2022/8663356]
12. Jia H, He J, Zhao L, et al. (2022) Combination of stem cell therapy and acupuncture to treat ischemic stroke: a prospective review. Stem Cell Res Ther, 13(1): 87. [DOI:10.1186/s13287-022-02761-y]
13. Zhan Y, Pei J, Wang J, et al. (2023) Motor function and fALFF modulation in convalescent-period ischemic stroke patients after scalp acupuncture therapy: a multi-centre randomized controlled trial. Acupunct Med, 41(2): 86-95. [DOI:10.1177/09645284221086289]
14. Qin S, Zhang Z, Zhao Y, et al. (2022) The impact of acupuncture on neuroplasticity after ischemic stroke: a literature review and perspectives. Front Cell Neurosci. 16: 817732. [DOI:10.3389/fncel.2022.817732]
15. Diao Q, Liu J, Wang C, et al. (2017) Gray matter volume changes in chronic subcortical stroke: A cross-sectional study. Neuroimage Clin, 14: 679-684. [DOI:10.1016/j.nicl.2017.01.031]
16. Miao P, Wang C, Li P, et al. (2018) Altered gray matter volume, cerebral blood flow and functional connectivity in chronic stroke patients. Neurosci Lett, 662: 331-338. [DOI:10.1016/j.neulet.2017.05.066]
17. Gauthier LV, Taub E, Mark VW, et al. (2012) Atrophy of spared gray matter tissue predicts poorer motor recovery and rehabilitation response in chronic stroke. Stroke, 43(2): 453-7. [DOI:10.1161/STROKEAHA.111.633255]
18. Lang Y, Li KS, Yang JY, et al. (2020) [Effect of acupuncture at the anterior oblique parietotemporal line on gray matter remodeling in patients with hemiplegia of cerebral infarction]. Zhen Ci Yan Jiu, 45(2): 141-7.
19. Wu P, Zhou YM, Liao CX, et al. (2018) Structural Changes Induced by Acupuncture in the Recovering Brain after Ischemic Stroke. Evid Based Complement Alternat Med, 2018: 5179689. [DOI:10.1155/2018/5179689]
20. Zhao N, Zhang J, Qiu M, et al. (2018) Scalp acupuncture plus low-frequency rTMS promotes repair of brain white matter tracts in stroke patients: A DTI study. J Integr Neurosci, 17(1): 61-69. [DOI:10.3233/JIN-170043]
21. Shen Y, Li M, Wei R, et al. (2012) Effect of acupuncture therapy for postponing Wallerian degeneration of cerebral infarction as shown by diffusion tensor imaging. J Altern Complement Med, 18(12): 1154-60. [DOI:10.1089/acm.2011.0493]
22. Kim MS, Moon BS, Ahn JY, et al. (2022) Elucidating the mechanisms of post-stroke motor recovery mediated by electroacupuncture using diffusion tensor tractography. Front Neurol, 13: 888165. [DOI:10.3389/fneur.2022.888165]
23. Tae WS, Ham BJ, Pyun SB, et al. (2018) Current Clinical Applications of Diffusion-Tensor Imaging in Neurological Disorders. J Clin Neurol, 14(2): 129-140. [DOI:10.3988/jcn.2018.14.2.129]
24. Di Pino G, Pellegrino G, Assenza G, et al. (2014) Modulation of brain plasticity in stroke: a novel model for neurorehabilitation. Nat Rev Neurol, 10(10): 597-608. [DOI:10.1038/nrneurol.2014.162]
25. Salehi Dehno N, Kamali F, Shariat A, et al. (2022) Comparison of Transcallosal Inhibition Between Hemispheres and Its Relationship with Motor Behavior in Patients with Severe Upper Extremity Impairment After Subacute Stroke. J Stroke Cerebrovasc Dis, 31(6): 106469. [DOI:10.1016/j.jstrokecerebrovasdis.2022.106469]
26. Rossini PM, Burke D, Chen R, et al. (2015) Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee. Clin Neurophysiol, 126(6): 1071-1107. [DOI:10.1016/j.clinph.2015.02.001]
27. Belyk M, Banks R, Tendera A, et al. (2021) Paradoxical facilitation alongside interhemispheric inhibition. Exp Brain Res, 239(11): 3303-3313. [DOI:10.1007/s00221-021-06183-9]
28. Wang P, Meng C, Yuan R, et al. (2020) The Organization of the Human Corpus Callosum Estimated by Intrinsic Functional Connectivity with White-Matter Functional Networks. Cereb Cortex, 30(5): 3313-3324. [DOI:10.1093/cercor/bhz311]
29. Quiroz-González S, Torres-Castillo S, López-Gómez RE, et al. (2017) Acupuncture Points and Their Relationship with Multireceptive Fields of Neurons. J Acupunct Meridian Stud, 10(2): 81-89. [DOI:10.1016/j.jams.2017.01.006]
30. Soulard J, Huber C, Baillieul S, et al. (2020) ISIS-HERMES Group. Motor tract integrity predicts walking recovery: A diffusion MRI study in subacute stroke. Neurology, 94(6): e583-e593. [DOI:10.1212/WNL.0000000000008755]
31. Yang FX, Gao JY, Liu G, et al. (2021) [Effect of tiaoren tongdu acupuncture method on fractional anisotropy of diffusion densor imaging and upper extremity motor function after cerebral infarction]. Zhen Ci Yan Jiu, 46(7): 610-5.
32. Darwish HS, ElShafey R, Kamel H (2021) Prediction of Motor Recovery after Stroke by Assessment of Corticospinal Tract Wallerian Degeneration Using Diffusion Tensor Imaging. Indian J Radiol Imaging, 31(1): 131-137. [DOI:10.1055/s-0041-1729671]
33. Hu LN, Tian JX, Gao W, et al. (2018) Electroacupuncture and moxibustion promote regeneration of injured sciatic nerve through Schwann cell proliferation and nerve growth factor secretion. Neural Regen Res, 13(3): 477-483. [DOI:10.4103/1673-5374.228731]
34. Nocera G and Jacob C (2020) Mechanisms of Schwann cell plasticity involved in peripheral nerve repair after injury. Cell Mol Life Sci, 77(20): 3977-3989. [DOI:10.1007/s00018-020-03516-9]
35. Liu H, Jiang Y, Wang N, et al. (2021) Scalp acupuncture enhances local brain regions functional activities and functional connections between cerebral hemispheres in acute ischemic stroke patients. Anat Rec (Hoboken), 304(11): 2538-2551. [DOI:10.1002/ar.24746]
36. Chen SQ, Cai DC, Chen JX, et al. (2020) Altered Brain Regional Homogeneity Following Contralateral Acupuncture at Quchi (LI 11) and Zusanli (ST 36) in Ischemic Stroke Patients with Left Hemiplegia: An fMRI Study. Chin J Integr Med, 26(1): 20-25. [DOI:10.1007/s11655-019-3079-6]
37. Adhikari BM, Hong LE, Zhao Z, et al. (2022) Cerebral blood flow and cardiovascular risk effects on resting brain regional homogeneity. Neuroimage, 262: 119555. [DOI:10.1016/j.neuroimage.2022.119555]
38. Li Z, Zhu Y, Childress AR, et al. (2012) Relations between BOLD fMRI-derived resting brain activity and cerebral blood flow. PLoS One, 7(9): e44556. [DOI:10.1371/journal.pone.0044556]
39. Xin JJ, Gao JH, Wang YY, et al. (2017) Antihypertensive and Antihypertrophic Effects of Acupuncture at PC6 Acupoints in Spontaneously Hypertensive Rats and the Underlying Mechanisms. Evid Based Complement Alternat Med, 2017: 9708094. [DOI:10.1155/2017/9708094]
40. Li J, He J, Du Y, et al. (2014) Electroacupuncture improves cerebral blood flow and attenuates moderate ischemic injury via Angiotensin II its receptors-mediated mechanism in rats. BMC Complement Altern Med, 14: 441. [DOI:10.1186/1472-6882-14-441]
41. Zhang J, Li Z, Li Z, et al. (2021) Progress of Acupuncture Therapy in Diseases Based on Magnetic Resonance Image Studies: A Literature Review. Front Hum Neurosci, 15: 694919. [DOI:10.3389/fnhum.2021.694919]
42. Sun ZG, Pi YL, Zhang J, et al. (2019) Effect of acupuncture at ST36 on motor cortical excitation and inhibition. Brain Behav, 9(9): e01370. [DOI:10.1002/brb3.1370]
43. Zhang J, Lu C, Wu X, et al. (2021) Neuroplasticity of Acupuncture for Stroke: An Evidence-Based Review of MRI. Neural Plast, 2021: 2662585. [DOI:10.1155/2021/2662585]
44. Lu M, Du Z, Zhao J, et al. (2023) Neuroimaging mechanisms of acupuncture on functional reorganization for post-stroke motor improvement: a machine learning-based functional magnetic resonance imaging study, 17: 1143239. [DOI:10.3389/fnins.2023.1143239]
45. Han X, Bai L, Sun C, et al. (2019) Acupuncture Enhances Communication between Cortices with Damaged White Matters in Poststroke Motor Impairment. Evid Based Complement Alternat Med, 2019: 4245753. [DOI:10.1155/2019/4245753]
46. Vergani F, Ghimire P, Rajashekhar D, et al. (2021) Superior longitudinal fasciculus (SLF) I and II: an anatomical and functional review. J Neurosurg Sci, 65(6): 560-565. [DOI:10.23736/S0390-5616.21.05327-3]
47. Ning Y, Li K, Fu C, et al. (2017) Enhanced Functional Connectivity between the Bilateral Primary Motor Cortices after Acupuncture at Yanglingquan (GB34) in Right-Hemispheric Subcortical Stroke Patients: A Resting-State fMRI Study. Front Hum Neurosci, 11: 178. [DOI:10.3389/fnhum.2017.00178]
48. Li Y, Wang Y, Liao C, et al. (2017) Longitudinal Brain Functional Connectivity Changes of the Cortical Motor-Related Network in Subcortical Stroke Patients with Acupuncture Treatment. Neural Plast, 2017: 5816263. [DOI:10.1155/2017/5816263]
49. Lin D, Gao J, Lu M, et al. (2023) Scalp acupuncture regulates functional connectivity of cerebral hemispheres in patients with hemiplegia after stroke. Front Neurol, 14: 1083066. [DOI:10.3389/fneur.2023.1083066]
50. Liu H, Chen L, Zhang G, et al. (2020) Scalp Acupuncture Enhances the Functional Connectivity of Visual and Cognitive-Motor Function Network of Patients with Acute Ischemic Stroke. Evid Based Complement Alternat Med, 2020: 8836794. [DOI:10.1155/2020/8836794]
51. Fu CH, Li KS, Ning YZ, et al. (2017) Altered effective connectivity of resting state networks by acupuncture stimulation in stroke patients with left hemiplegia: A multivariate granger analysis. Medicine (Baltimore), 96(47): e8897. [DOI:10.1097/MD.0000000000008897]
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Wu Y, Li J, Pei L. Uncovering the mechanisms by which acupuncture improves motor function after stroke through neuroplasticity revealed by magnetic resonance imaging techniques. Int J Radiat Res 2024; 22 (3) :647-655
URL: http://ijrr.com/article-1-5614-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 22, Issue 3 (7-2024) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.06 seconds with 50 queries by YEKTAWEB 4714