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Showing 15 results for Jin
J.f. Pei, Ph.d., J. Zhang, D.c. Jin, B.l. Miao,
Volume 22, Issue 1 (1-2024)
Abstract
Background: A substantial number of women throughout the world are affected with breast cancer, a dangerous and sometimes deadly condition. The creation of precise prediction models to determine the chance of survival in breast cancer patients has drawn increasing attention in recent years. The use of backpropagation neural networks (BPNNs) to forecast breast cancer patient survival is investigated in this study. Materials and Methods: A total of 198 patients with early breast cancer who were treated in our hospital were selected The control group received traditional breast cancer radical mastectomy and radiotherapy, and the experimental group received mastoscopy Adjuvant nipple-areola complex (NAC) modified radical mastectomy combined with prosthesis implantation and radiotherapy was used to compare the surgical conditions, postoperative complications, patient satisfaction and living standards in two groups. Results: The range of change was small, and the difference was statistically significant (P<0.05) ;in the laboratory group, patient dissatisfaction was noticeably raised over that in the standard group, and the discrepancy was politically sensitive (P<0.05); over that in the control group, the scores of all dimensions of survival quality were appreciably raised over that in the laboratory group, and the correlation was striking (P<0.05). Survival quality was greatly expanded in the experimental and postoperative groups at 3 and 6 months postoperatively before surgery, and the difference was statistically significant (P<0.05); Conclusion: The study demonstrates that BPNN-based predictive models can be useful tools for improving the accuracy of breast cancer survival rate prediction, thus aiding in more effective treatment planning and decision-making for breast cancer patients.
X. Tian, Z. Shen, S. Wang, X. Liu, H. Luo, Ph.d., F. Jin,
Volume 22, Issue 2 (4-2024)
Abstract
Background: This paper aimed to investigate the radiation dosimetry and dose deposition to the surrounded organs at risk (OARs) with different radial and longitudinal margins based on the normal tissue complication probability (NTCP) and dose-volume histogram (DVH) methods. Materials and Methods: Fifteen patients with histologically diagnosed esophageal cancer were retrospectively selected. From the clinical target volume (CTV), eight planning target volumes (PTV) were expanded for each patient, with one group of four radial margins (3mm, 5mm, 7mm, 10mm) and the other group of four longitudinal margins (3mm, 5mm, 7mm, 10mm). Then, eight plans with the prescription dose of 50.4Gy were designed in the tomotherapy system. Within each group, doses for the OARs and NTCP-based risk of pneumonitis and pericardial disease were compared. Results: Almost all the dose parameters in both groups, except for the Dmax (maximum dose) of the spinal cord in the longitudinal direction, showed significant linearly increasing trends with the expansion of margins. For same dose parameters, the increased slopes in the radial direction were larger than those in the longitudinal. Heart V30Gy (the percent volume of receiving 30Gy) grew fastest compared to other clinical constraint indexes in both groups, and the most significant difference in the risk of pneumonitis was observed in the radial group when the margin was expanded from 3 to 10mm. Conclusions: In order to lower the likelihood of radiation-related toxicity, radial margin expansion should be more strictly controlled in the radiotherapy of esophageal cancer with tomotherapy.
Z. Song, M. Zhuang, Z. Jin, Y. Gao, B. Bian,
Volume 22, Issue 2 (4-2024)
Abstract
Background: Clinical stage and the ability to achieve comprehensive treatment were the prognostic features of thymoma. In the present study, we aimed to analyze the efficacy of different types of therapy in patients with Masaoka-Koga stage III thymoma. Materials and Methods: From 2001 to 2018, patients newly diagnosed with thymoma was retrospectively analyzed. The c2test was used to evaluate patient characteristics, the Kaplan-Meier method was used to calculate overall survival (OS), log-rank method was applied to examine the difference between groups, and Cox regression was used to analysis the potential prognostic factors of OS. Results: The median follow-up time was 50 months (range: 3-221 months), and median OS was 51 (range: 3-221) months. The radical surgery group had a significantly better OS than the palliative surgery group. The 5- year, 10-year OS were 88.2%, 74.4% in the radical surgery group, whereas the 5- year, 10-year OS were 51.8% and 32.4% in the palliative group. The 5-year OS in surgery followed by adjuvant radiotherapy group was higher than that of surgery alone group (82.8% vs 55.8%, P=0.033); similarly, the 10-year OS of the two groups were 64.2% and, 50.2%, respectively (P＜0.05). Multivariate analysis revealed that age < 50 years (HR [hazard ratio]: 0.264), radical resection (HR:0.134, P=0.000), and surgery combined with radiotherapy (HR:2.778, P=0.009) were independently associated with better OS. Conclusion: In Masaoka-Koga stage III thymoma, patients treated with radical surgery was capable of achieving better OS than patients treated with palliative surgery. Moreover, radical surgery was an independent factor of prognosis.
J. Zhao, W. Chen, C. Li, H. Xiao, Y. Jin, Y. Wang, M.d., J. Gao,
Volume 23, Issue 1 (1-2025)
Abstract
Background: To investigate the efficacy of laparoscopic combined with microwave ablation therapy in treating multiple uterine fibroids and its impact on patients' quality of life. Materials and Methods: This study included a total of 100 patients with uterine fibroids, divided into a laparoscopic group (50 cases) and a laparoscopic combined with microwave ablation group (50 cases), treated with either laparoscopic surgery alone or laparoscopic combined with microwave ablation therapy. General information of the patients, MRI images before and after treatment, contrast-enhanced ultrasound before and after treatment, intraoperative blood loss, operation time, length of hospital stay, time to postoperative ambulation, VAS score, and ovarian function were collected and analyzed. Results: Compared with laparoscopic surgery alone, the laparoscopic combined with microwave ablation group had lower postoperative pain scores, less intraoperative blood loss, and faster postoperative recovery. There was no significant difference in ovarian function indicators after surgery compared with before surgery, indicating no difference in ovarian function and reserve between the two surgical methods. Additionally, the total effective rate of the combined treatment group reached 98%, significantly higher than the 92% in the laparoscopic group. Imaging analysis showed that the structure of surrounding tissues and vascular layout were restored closer to the normal state after combined treatment. Conclusion: Laparoscopic combined with microwave ablation therapy shows superior efficacy and safety in treating multiple uterine fibroids compared to laparoscopic surgery alone, making it an effective method for treating multiple uterine fibroids, worthy of further clinical promotion and application.
Y. Yang, S. Ge, Y. Chen, C.p. Jing,
Volume 23, Issue 1 (1-2025)
Abstract
Background: To explore the feasibility of using various ultra-low contrast flow rates on the coronary CTA (CCTA) when the tube voltage is set at 80KV automatically on 3rd-generation dual-source CT. Materials and Methods: A total of 180 patients with suspected coronary atherosclerotic disease were randomly divided into two groups, each subdivided into seven BMI-based subgroups (≤ 25, 25-26, 26-27, 27-28, 28-29, 29-30, > 30). The experimental group (A) used individualized injection rates (2.8-3.4 ml/s) with 350 mg I/ml contrast agent based on BMI, with a fixed injection time of 10s. The control group (B) used a fixed injection rate of 4.0 ml/s and a fixed injection time of 12s. Both groups employed prospective ECG-gated scanning. Image quality, effective radiation dose, and contrast agent dosage were compared using the Student's t-test. Results: In Group B, the coronary artery CT value exceeded the optimal diagnostic range (300-450 HU) recommended by experts. Group A had significantly lower CT values, SNR, and CNR compared to Group B (P < 0.05), but the enhancement in Group A was closer to the optimal diagnostic range. There was no significant difference in subjective image scores between the groups (P > 0.05), with consistent scoring between two directors (ICC: 0.612-0.852). Both groups had similar effective doses (P > 0.05). The contrast agent dosage in Group A was significantly lower than in Group B (P < 0.05). Conclusion: The optimized contrast injection scheme can significantly reduce the amount of contrast agent and obtain better image quality.
Background: To explore the feasibility of using various ultra-low contrast flow rates on the coronary CTA (CCTA) when the tube voltage is set at 80KV automatically on 3rd-generation dual-source CT. Materials and Methods: A total of 180 patients with suspected coronary atherosclerotic disease were randomly divided into two groups, each subdivided into seven BMI-based subgroups (≤ 25, 25-26, 26-27, 27-28, 28-29, 29-30, > 30). The experimental group (A) used individualized injection rates (2.8-3.4 ml/s) with 350 mg I/ml contrast agent based on BMI, with a fixed injection time of 10s. The control group (B) used a fixed injection rate of 4.0 ml/s and a fixed injection time of 12s. Both groups employed prospective ECG-gated scanning. Image quality, effective radiation dose, and contrast agent dosage were compared using the Student's t-test. Results: In Group B, the coronary artery CT value exceeded the optimal diagnostic range (300-450 HU) recommended by experts. Group A had significantly lower CT values, SNR, and CNR compared to Group B (P < 0.05), but the enhancement in Group A was closer to the optimal diagnostic range. There was no significant difference in subjective image scores between the groups (P > 0.05), with consistent scoring between two directors (ICC: 0.612-0.852). Both groups had similar effective doses (P > 0.05). The contrast agent dosage in Group A was significantly lower than in Group B (P < 0.05). Conclusion: The optimized contrast injection scheme can significantly reduce the amount of contrast agent and obtain better image quality.
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