en Radiation Biology Radiation Biology گزارش کوتاه Short Report <p><strong>Background:</strong> Radiation-induced bystander effect is a response which results in damage in non-irradiated cells in response to signals from the irradiated cells. The aim of the present study was to investigate microwave-induced bystander effect from a GSM mobile phone simulator on induction of apoptosis in Jurkat cell line. <strong>Materials and Methods:</strong> Jurkat cells were divided into three groups of non-irradiated, exposed and bystander (medium transfer from the irradiated cells). The exposed group was subjected to irradiation from GSM mobile simulator for 2h and 12h the medium from irradiated cells was then transferred to the bystander cells. Apoptosis rate was measured12 and 24 hours after treatment by Annex in V 7-AAD kit using flow cytometry. <strong> Results:</strong> Apoptosis was observed in both exposed and bystander cells of Jurkat cell line. The difference among non-irradiated, exposed and bystander cell groups was significant (p<0.05). <strong>Conclusion:</strong> From the obtained results it can be concluded that microwave radiation exposure in Jurkat cells leads to a significant increase in the apoptosis rate not only in the exposed cells but also in the bystander cells.</p> Apoptosis, bystander effect, microwave, radiofrequency (RF), Jurkat cell line 181 186 http://ijrr.com/browse.php?a_code=A-10-1-558&slc_lang=en&sid=1 S.M.J. Mortazavi 790031947532846009776 790031947532846009776 No Department of Medical Physics and Medical Engineering , School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran N. Erfani erfanin@sums.ac.ir 790031947532846009777 790031947532846009777 Yes Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran H. Mozdarani 790031947532846009778 790031947532846009778 No Department of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran R. Azmoonfar 790031947532846009779 790031947532846009779 No Radiology Department, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran N. Shokrpour 790031947532846009780 790031947532846009780 No School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran