en Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background</span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-weight:bold"><span style="language:en-US">:</span></span></span></span></span> <span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">To probe the effects of computed tomography (CT) positioning-guided puncture and drainage of cerebral hemorrhage. </span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-GB">Material and Methods: </span></span></span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">Totally 120 patients with hypertensive cerebral hemorrhage (HCH) in our hospital from February 2022 to January 2023 enrolled in this study. Patients were randomized into observation group (OG) and control group (CG), including 60 cases in each group. Patients in the CG were given conservative treatment. Patients in the OG were given CT guided puncture and drainage of intracerebral hemorrhage. The effects of different treatment on clinical efficacy, daily living ability, motor function of limbs, quality of life, incidence of postoperative complications and patient satisfaction were compared. </span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-GB">Results: </span></span></span></span></span></span><span lang="en-GB" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-GB">The total clinical response rate in the OG reached 93.33%, which was significantly higher compared with the 78.33% in CG (</span></span></span></span><span lang="el" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:el">&chi;2=5.55, </span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-US">P<0.05). After treatment, daily living ability and motor function scores were elevated in both groups, and were higher after CT positioning-guided puncture than conservative treatment (P<0.05). The score of social relations, mental function, mental vitality and physical function were higher while the complication rate was lower in the OG in comparison with the CG (P<0.05). Moreover, OG also showed higher patient satisfaction rate than the CG (96.67% VS 78.33%), with statistical significance (</span></span></span></span><span lang="el" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:el">&chi;2=9.22, </span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-US">P<0.05). </span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusion: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:black"><span style="language:en-US">CT positioning-guided puncture and drainage is a reliable and effective approach to attenuate the hematoma, improve the life quality of patients with intracerebral hemorrhage, with better clinical response and less complications relative to the conservative treatment.</span></span></span></span></span></span></span></span></span></span></div> Computed tomography, puncture and drainage, intracerebral hemorrhage, hypertension. 43 48 http://ijrr.com/browse.php?a_code=A-10-1-1136&slc_lang=en&sid=1 Rong Cai 7900319475328460025853 7900319475328460025853 No Department of Operating Center, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, China