en Radiation Biology Radiation Biology مطالعه موردي Case Report <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Medulloepithelioma (MEPL) of the central nervous system (CNS) was once considered as a rare malignant embryonic tumor of the nervous system. The new classification of central nervous system tumors classified it as an Embryonal tumor with multilayered rosettes (ETMR), and its diagnosis depends on immunophenotype and molecular detection in addition to histology. This kind of tumor rarely occurs in adults, and the best treatment is uncertain. This case reports a case of adult MEPL, which mainly shows numbness of limbs. Magnetic resonance imaging (MRI) of the head showed a well-defined tumor near the meninges of the parietal lobe with small cystic changes, which was unevenly enhanced on enhanced scanning. The patient&#39;s local recurrence was confirmed within 18 months after complete resection of the tumor by simple operation, and radiotherapy and chemotherapy were given after the second operation. There was no disease progress 32 months after operation. According to our report, it can be speculated that operation, craniospinal radiotherapy (CSI) plus tumor bed boost and high dose chemotherapy are of great value to improve the prognosis of MEPL/ETMR.</span></span></span></span></span></span></span></span></span></div> MEPL, ETMR, Treatment, Therapeutic Radiotherapy. 777 801 http://ijrr.com/browse.php?a_code=A-10-1-1243&slc_lang=en&sid=1 J. Li lijlzu@163.com 7900319475328460028141 7900319475328460028141 Yes Department of Radiotherapy, The Second Hospital of Lanzhou University, Lanzhou, China Y. Liu 7900319475328460028142 7900319475328460028142 No Department of Neurology, The Second Hospital of Lanzhou University, Lanzhou, China