International Journal of Radiation Research

en Comparative analysis of the efficacy of transanal endoscopic microsurgery and endoscopic submucosal dissection in the treatment of rectal tumors Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: The purpose of this study was to compare the efficacy of endoscopic submucosal dissection (ESD) and transanal endoscopic microsurgery (TEM) in the treatment of rectal cancers. Materials and Methods: Between January 2021 and January 2023, one hundred patients with rectal tumors came to our hospital. They were randomized into two groups: the ESD group (n = 50) and the TEM group (n = 50). We made comparisons between hospital stay, antibiotic usage rate, intraoperative hemorrhage, and surgery time. Additionally, we assessed the complete tumor resection rate, tumor residual rate, recurrence rate, time of first anal discharge, and serum levels of motilin (MTL) and gastrin (GAS). A 6-month follow-up period was also used to compare the two groups' complication occurrence. Results: In the ESD group, surgical time, antibiotic usage rate, and hospital stay were significantly reduced compared to the TEM group (P < 0.05). No statistically significant difference in intraoperative bleeding was observed (P > 0.05). Complete tumor resection rate, tumor residual rate, recurrence rate, first anal discharge time, serum MTL and GAS levels, and incidence of complications showed no significant differences between the two groups (P > 0.05). Conclusion: TEM and ESD demonstrate comparable efficacy in treating rectal tumors. However, ESD exhibits advantages over TEM, including shorter surgical and hospitalization times and lower antibiotic application rates. These findings offer valuable insights for the clinical management of rectal tumors.</div> Rectal neoplasms, endoscopic submucosal dissection, transanal endoscopic microsurgery, antibiotic usage. 1059 1065 http://ijrr.com/browse.php?a_code=A-10-1-1276&slc_lang=en&sid=1 Zh. Wuqiang 7900319475328460028823 7900319475328460028823 No Department of surgery, Shexian Hospital, Handan, Hebei, P.R. China Zh. Haiyong 7900319475328460028824 7900319475328460028824 No The Second Hospital of Hebei Medical University, Shijiazhuang, China C. Yahong 7900319475328460028825 7900319475328460028825 No Department of surgery, Shexian Hospital, Handan, Hebei, P.R. China F. Yingke 7900319475328460028826 7900319475328460028826 No Department of surgery, Shexian Hospital, Handan, Hebei, P.R. China Zh. Juping Jupingzh@163.com 7900319475328460028827 7900319475328460028827 No Department of surgery, Shexian Hospital, Handan, Hebei, P.R. China