International Journal of Radiation Research

en Study on the relationship between abnormal imaging manifestations of adipose tissue around the primary tumor of colon cancer, genomics and recurrence probability Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: This study aims to explore the relationship between abnormal imaging manifestations of adipose tissue around the primary tumor of colon cancer, genomics, and recurrence probability, in order to deepen our understanding of the pathological characteristics and molecular mechanisms of colon cancer. Materials and Methods: We collected imaging data of a group of colon cancer patients and obtained relevant genetic information through genomic analysis. Statistical methods were used to quantitatively analyze the abnormal imaging manifestations of adipose tissue around the primary tumor of colon cancer. At the same time, the patient's clinical course is followed to assess the probability of recurrence. Results: The study found that abnormal imaging manifestations of adipose tissue surrounding primary colon cancer tumors were significantly associated with specific gene mutations. Some specific genetic mutations are positively correlated with abnormal signals on imaging, while others are negatively correlated. Furthermore, after long-term follow-up, we observed a relatively higher probability of recurrence in patients with genetic variants associated with imaging abnormalities. Conclusion: The abnormal imaging manifestations of adipose tissue around the primary tumor of colon cancer can be used as one of the auxiliary indicators for molecular classification of colon cancer. The association between specific genetic variants and imaging abnormalities suggests possible molecular mechanisms and provides new clues for personalized treatment. Furthermore, the association of imaging abnormalities with recurrence probability emphasizes its potential importance in prognostic assessment.</div> Colon cancer, adipose tissue, imaging, genomics. 103 109 http://ijrr.com/browse.php?a_code=A-10-1-1298&slc_lang=en&sid=1 Q. Wang 7900319475328460029469 7900319475328460029469 No Department of Basic Medical Sciences, Tianjin Medical College, Tianjin, China Z. Wang 7900319475328460029470 7900319475328460029470 No Siemens Healthineers, Beijing, China L. Liu 7900319475328460029471 7900319475328460029471 No Department of Radiology, Guangzhou First People’s Hospital, School of Medicine, South China University of Technology, Guangzhou, China H. Wang 7900319475328460029472 7900319475328460029472 Yes Department of General Surgery, Tianjin Haihe Hospital, Tianjin, China