International Journal of Radiation Research

other A meta-analysis examining the risk factors associated with pneumothorax during CT-guided percutaneous lung biopsy Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: The study aimed to systematically evaluate the risk factors for pneumothorax after computed tomography (CT)-guided percutaneous lung biopsy. Materials and Methods: We conducted a search of several databases, including PubMed, Embase, the Cochrane Library, Web of Science, and CNKI, until May 2021, focusing on research related to risk factors for pneumothorax following CT-guided percutaneous lung biopsy. After screening and extracting the data, we conducted a meta-analysis using RevMan software (version 5.3) to calculate the odds ratio (OR) and 95% confidence interval (CI) for each relevant risk factor. Statistical significance was set at P<0.05. Results: Our study included 28 articles and 16,667 patients who underwent CT-guided lung biopsy, of whom 4,566 patients developed pneumothorax (27.40%). Our results showed that the incidence of pneumothorax was lower in the group with pulmonary nodules ≥ 2 cm, and the difference was statistically significant (OR=0.61, 95% CI=0.43–0.86, P=0.004). Additionally, patients with emphysema had a higher risk of developing a pneumothorax after the procedure, and the difference was statistically significant (OR=2.5, 95% CI=1.62–3.87, P<0.0001). Correlation analysis of sex, lung nodule size, needle track length, and CT-guided lung nodule biopsy showed no significant differences (P>0.05). Conclusion: Our findings indicate that pulmonary nodules smaller than 2 cm and emphysema significantly increase the risk of pneumothorax after puncture. Clinicians should be vigilant in monitoring patients with these risk factors after the procedure.</div> CT-guided percutaneous lung biopsy, pulmonary nodules, pneumothorax, risk factors, meta-analysis. 233 238 http://ijrr.com/browse.php?a_code=A-10-1-1315&slc_lang=other&sid=1 J. Xiaoxing 7900319475328460029777 7900319475328460029777 No Department of Radiology, Medical Community of Linhai Second People's Hospital, Linhai, China W. Dongnv 7900319475328460029778 7900319475328460029778 No Department of Radiology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China W. Yitian 7900319475328460029779 7900319475328460029779 No Department of Radiology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China M. Ling 7900319475328460029780 7900319475328460029780 No Key Laboratory of evidence-based Radiology of Taizhou, Linhai, Zhejiang, China J. Wenbin wb.j@163.com 7900319475328460029781 7900319475328460029781 Yes Department of Radiology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China Y. Shuzong ysz9277@163.com 7900319475328460029782 7900319475328460029782 No Department of Radiology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China