en Radiation Biology Radiation Biology مطالعه موردي Case Report <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background:</span></span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">To investigate the correlation between magnetic resonance imaging (MRI) imaging characteristics and serum markers carcinoembryonic antigen (CEA), carbohydrate antigen 199 (CA199), and carbohydrate antigen 125 (CA125) levels in ovarian cancer patients. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Materials and Methods: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">A retrospective analysis of 85 patients with ovarian cancer diagnosed by postoperative pathological results in our hospital was carried out. MRI imaging data and hematological indexes of patients were collected to analyze the relationship between imaging characteristics of ovarian cancer patients and serum CEA, CA199, CA125 levels. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Results: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">The main morphology of ovarian cancer was irregular, with solid lesions and visible septal changes and wall nodules. After enhancement, the septal or parietal nodules also significantly enhanced, accompanied by abdominal effusion, peritoneal metastasis, and lymph node metastasis. Serum CEA (66.33&plusmn;6.54) g/ml, CA199 (185.03&plusmn;20.71) U/ml, CA125 (224.62&plusmn;23.82) U/ml. The results of univariate analysis showed that patients with ovarian cancer wall nodules, peritoneal metastasis, and lymph node metastasis had statistically significant differences in serum CEA, CA199, and CA125 concentrations (P<0.05). Pearson&#39;s results showed that wall nodules, peritoneal metastasis, and lymph node metastasis were positively correlated with serum CEA, CA199, and CA125 levels, respectively (P<0.05). </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusion: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Ovarian cancer MRI has certain characteristics related to CEA, CA199, CA125 concentrations, which can be used to diagnose the prognosis of ovarian cancer.</span></span></span></span></span></span></span></span></span></div> Ovarian cancer, magnetic resonance imaging, serum tumor markers, lymph node metastasis. 513 519 http://ijrr.com/browse.php?a_code=A-10-1-1361&slc_lang=en&sid=1 X. Lu 7900319475328460031262 7900319475328460031262 No Department of Gynecology, The First People's Hospital of Zunyi, Zunyi, China S. Xie xsy419848977@163.com 7900319475328460031263 7900319475328460031263 Yes Department of Gynecology, The First People's Hospital of Zunyi, Zunyi, China D. Mou 7900319475328460031264 7900319475328460031264 No Department of Gynecology, The First People's Hospital of Zunyi, Zunyi, China M. Peng 7900319475328460031265 7900319475328460031265 No Department of Gynecology, The First People's Hospital of Zunyi, Zunyi, China