International Journal of Radiation Research

en Evaluation of clinical efficacy of ultrasound-guided joint injection of hypertonic glucose combined with blood flow restriction training in the treatment of rotator cuff injury Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;">Background: Rotator cuff injuries are common musculoskeletal conditions that impair shoulder function and quality of life. Conventional therapies often fail to address the biological and mechanical deficiencies of these injuries. This study evaluated the clinical efficacy of ultrasound-guided hypertonic glucose injections combined with blood flow restriction (BFR) training in managing rotator cuff injuries. Materials and Methods: A randomized controlled trial involving 120 patients with rotator cuff injuries was conducted. Participants were assigned to an experimental group (ultrasound-guided glucose injections with BFR training, n=60) or a control group (standard physical therapy, n=60). Pain, shoulder function, tendon thickness, range of motion (ROM), muscle strength, and patient-reported outcomes were assessed over 12 weeks using ultrasound imaging and validated scales (visual analog scale (VAS), Constant–Murley score (CMS), shoulder disability index (SDI), and American Shoulder and Elbow Surgeons (ASES) score). Results: The experimental group showed significant improvements compared to the control group, including reduced pain (VAS: -3.0, p<0.001), enhanced function (CMS: +29.5, p<0.001), increased ROM (+25°, p<0.001), decreased tendon thickness (-1.7 mm, p<0.001), and improved muscle strength (+2.8 kg, p<0.001). Patient-reported satisfaction and functionality (ASES: +33.4, p<0.001) were also higher in the experimental group. Conclusion: The combination of hypertonic glucose injections and BFR training is an effective approach for treating rotator cuff injuries. It provides significant pain relief, functional recovery, and structural improvements, which highlight its potential as a better alternative to conventional treatments. Further research is recommended to assess the long-term efficacy and refine the treatment protocols.</div> Rotator Cuff Injuries, hypertonic glucose, blood flow restriction training, ultrasound-guided, musculoskeletal rehabilitation. 651 658 http://ijrr.com/browse.php?a_code=A-10-1-1380&slc_lang=en&sid=1 F. Gu drgufen48050@hotmail.com 7900319475328460031650 7900319475328460031650 No Department of Ultrasound, Xijing Hospital, Fourth Military Medical University, Changle West Road, Xi’an, Shaanxi Province, China M. Deng 7900319475328460031651 7900319475328460031651 No Department of Ultrasound, Yuncheng Central Hospital, Shanxi Medical University, Hedong East Street, Yanhu District, Yuncheng, Shanxi Province, China Y. Zhao 7900319475328460031652 7900319475328460031652 No Department of Ultrasound, Xijing Hospital, Fourth Military Medical University, Changle West Road, Xi’an, Shaanxi Province, China X. Chen 7900319475328460031653 7900319475328460031653 No Department of Ultrasound, Xijing Hospital, Fourth Military Medical University, Changle West Road, Xi’an, Shaanxi Province, China L. An 7900319475328460031654 7900319475328460031654 No Department of Ultrasound, Xijing Hospital, Fourth Military Medical University, Changle West Road, Xi’an, Shaanxi Province, China Z. Zhao zhao900803zhen@hotmail.com 7900319475328460031655 7900319475328460031655 Yes Avic Xi’an Aircraft Industry Group Company Ltd, No.1 Xifei Avenue, Yanliang District, Xi’an, Shaanxi Province, China