en Radiation Biology Radiation Biology تحقيق بديع Original Research <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:newspaper"><span style="text-kashida-space:50%"><span style="line-height:119%"><span style="font-family:Calibri"><span style="color:black"><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Background:</span></span></span></span></span></span> <span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">The effects of electromagnetic radiation (EMR) on the body are an emerging field of research. The evidence supports the production of oxidative stress (OS) through EMR and the positive role of exercise in reducing liver damage. The evidence supports the production of OS through EMR and the positive role of exercise in reducing liver damage. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Materials and Methods: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">32 Wistar male rats were randomly divided into four groups: control, EMR, endurance training (ET), and EMR+ET. The ET and EMR+ET groups ran on the treadmill with the maximum speed and duration of 30 m/ min and 35 min, respectively (5 sessions/weeks, during four weeks). The ET and EMR+ ET groups were exposed to a 2.45GHZ Wi-Fi router for four weeks (4 h/day, 7days/weeks). Forty-eight hours after the last training session, the blood and liver tissue of the animals were sampled for histological, biochemical evaluations and measurement of oxidative stress markers. </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Results: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Histopathological findings confirmed the protective role of ET in rats exposed to EMR. The results showed that in the EMR group, the concentration of malondialdehyde (MDA) and the serum levels of liver enzymes (AST, ALT, and ALP) increased significantly, and the activity of antioxidant enzymes decreased significantly (P<0.05). In the ET and EMR+ET groups, compared to the EMR group, the concentration of MDA and the serum levels of liver enzymes significantly decreased, and the activity of antioxidant enzymes increased significantly (P<0.05). </span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="color:#1f497d"><span style="font-style:italic"><span style="font-weight:bold"><span style="language:en-US">Conclusion: </span></span></span></span></span></span><span lang="en-US" style="font-size:9.0pt"><span style="font-family:Calibri"><span style="language:en-US">Our findings show that ET can improve the state of OS and liver damage caused by EMR.</span></span></span></span></span></span></span></span></span></div> Endurance training, electromagnetic radiation, oxidative stress, transaminases, pathology. 1051 1056 http://ijrr.com/browse.php?a_code=A-10-1-1434&slc_lang=en&sid=1 H. Amiri 7900319475328460032515 7900319475328460032515 No Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran K. Rakhshan 7900319475328460032516 7900319475328460032516 No Department of Physiology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran F. Shabkhiz 7900319475328460032517 7900319475328460032517 No Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran R. Zeighami fard 7900319475328460032518 7900319475328460032518 No Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran N. Aboutaleb dr.nabotaleb@gmail.com 7900319475328460032519 7900319475328460032519 No Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran