[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
IJRR Information::
For Authors::
For Reviewers::
Subscription::
News & Events::
Web Mail::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
ISSN
Hard Copy 2322-3243
Online 2345-4229
..
Online Submission
Now you can send your articles to IJRR office using the article submission system.
..

AWT IMAGE

AWT IMAGE

:: Volume 21, Issue 4 (10-2023) ::
Int J Radiat Res 2023, 21(4): 713-717 Back to browse issues page
Effect of ultrasound-guided epidermal growth factor injection combined with carbon dioxide laser on treatment of facial acne scars
L. Liao , F. Lu
Department of Ultrasound, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu, 215008, China , fengxialu@126.com
Abstract:   (1490 Views)
Background: To determine the therapeutic effect of ultrasound-guided epidermal growth factor (EGF) injection combined with carbon dioxide laser on facial acne scars. Materials and Methods: One hundred patients with facial acne scars admitted to the dermatology department from October 2021 to October 2022 were selected as the subjects of this study. The observation group (OG) received ultrasound guided EGF injection combined with carbon dioxide 2 (CO2) laser treatment, and the control group (CG) received CO2 laser treatment alone. The clinical outcomes and the recovery time after treatment were recorded for both groups of patients. Quantitative skin analysis including skin spots, red mass, pores and wrinkles were performed before and after treatment by VISIA skin detector, and inflammatory factors levels were measured. Results: The pain duration, erythema duration, incrustation time, decrustation time and incidence of adverse reactions in the OG were lower than those in the CG, while the total efficiency of treatment was higher than that in the CG (P<0.05). In addition, the results of quantitative analysis of skin spots, red matter, pores and wrinkles were higher in the OG and inflammatory factors levels were lower in the CG after treatment (P<0.05). Conclusion: EGF combined with CO2 laser can effectively improve scarring symptoms and shorten the recovery period in patients with facial acne scars.
Keywords: Epidermal growth factor, ultrasonography, CO2 lasers, cicatrix, acne vulgaris.
Full-Text [PDF 584 kb]   (719 Downloads)    
Type of Study: Original Research | Subject: Radiation Biology
References
1. Hazarika N (2021) Acne vulgaris: New evidence in pathogenesis and future modalities of treatment. J Dermatolog Treat, 32(3): 277-285. [DOI:10.1080/09546634.2019.1654075] [PMID]
2. Mohsin N, Hernandez LE, Martin MR, et al. (2022) Acne treatment review and future perspectives. Dermatol Ther, 35(9): e15719. [DOI:10.1111/dth.15719] [PMID]
3. Baldwin H and Tan J (2021) Effects of diet on acne and its response to treatment. Am J Clin Dermatol, 22(1): 55-65. [DOI:10.1007/s40257-020-00542-y] [PMID] []
4. Habeshian KA and Cohen BA (2020) Current issues in the treatment of acne vulgaris. Pediatrics, 145(2): S225-S230. [DOI:10.1542/peds.2019-2056L] [PMID]
5. Xu Y and Deng Y (2018) Ablative fractional CO2 laser for facial atrophic acne scars. Facial Plast Surg, 34(2): 205-219. [DOI:10.1055/s-0037-1606096] [PMID]
6. Galal O, Tawfik AA, Abdalla N, Soliman M (2019) Fractional CO2 laser versus combined platelet-rich plasma and fractional CO2 laser in treatment of acne scars: Image analysis system evaluation. J Cosmet Dermatol, 18(6): 1665-1671. [DOI:10.1111/jocd.12909] [PMID]
7. Kwon HH, Yang SH, Lee J, et al. (2020) Combination treatment with human adipose tissue stem cell-derived exosomes and fractional CO2 laser for acne scars: A 12-week prospective double-blind randomized split-face study. Acta Derm Venereol, 100(18): adv00310. [DOI:10.2340/00015555-3666] [PMID] []
8. Lin L, Liao G, Chen J, Chen X (2022) A systematic review and meta-analysis on the effects of the ultra-pulse CO2 fractional laser in the treatment of depressed acne scars Ann Palliat Med, 11(2): 743-755. [DOI:10.21037/apm-22-70] [PMID]
9. Li MK, Liu C, Hsu JTS (2021) The Use of Lasers and Light Devices in Acne Management: An Update Am J Clin Dermatol, 22(6):785-800. [DOI:10.1007/s40257-021-00624-5] [PMID]
10. Kim DH, Yang JH, Cho SI, et al. (2022) Clinical and histological effects of topical epidermal growth factor on acne and acne scars. Dermatology, 22(6): 785-800. [DOI:10.1159/000521294] [PMID]
11. Ratanapokasatit Y and Sirithanabadeekul P (2022) The efficacy and safety of epidermal growth factor combined with fractional carbon dioxide laser for acne scar treatment: A split-face trial. J Clin Aesthet Dermatol, 22(6): 785-800.
12. Oge LK, Broussard A, Marshall MD (2019) Acne vulgaris: Diagnosis and treatment. Am Fam Physician, 100(8): 475-484.
13. Dreno B, Khammari A, Orain N, et al. (2007) ECCA grading scale: an original validated acne scar grading scale for clinical practice in dermatology Dermatology, 214(1): 46-51. [DOI:10.1159/000096912] [PMID]
14. Kim JK, Park JY, Shin YH, et al. (2022) Reliability and validity of Vancouver Scar Scale and Withey score after syndactyly release. J Pediatr Orthop B, 31(6): 603-607. [DOI:10.1097/BPB.0000000000000983] [PMID]
15. Hauk L (2017) Acne Vulgaris: Treatment Guidelines from the AAD. Am Fam Physician, 95(11): 740-741.
16. Heng AHS and Chew FT (2020) Systematic review of the epidemiology of acne vulgaris Sci Rep, 10(1): 5754. [DOI:10.1038/s41598-020-62715-3] [PMID] []
17. Kurokawa I and Nakase K (2020) Recent advances in understanding and managing acne F1000Res, 9. [DOI:10.12688/f1000research.25588.1] [PMID] []
18. Aydingoz IE, Tukenmez Demirci G, Agirbasli D, et al. (2021) The investigation of the amounts and expressions of epidermal growth factor epidermal growth factor receptor and epidermal growth factor receptor gene polymorphisms in acne vulgaris, J Cosmet Dermatol, 20(1): 346-351. [DOI:10.1111/jocd.13498] [PMID]
19. Dall'oglio F, Puglisi DF, Nasca MR, Micali G (2020) Acne fulminans G. Ital Dermatol Venereol, 155(6): 711-718. [DOI:10.23736/S0392-0488.20.06711-5] [PMID]
20. Do TH, Ma F, Andrade PR, Teles R, et al. (2022) TREM2 macrophages induced by human lipids drive inflammation in acne lesions. Sci Immunol, 7(73): eabo2787. [DOI:10.1126/sciimmunol.abo2787] [PMID] []
21. Zhang L, Yang J, Liu X, et al. (2021) 5-Aminolaevulinic acid photodynamic therapy amplifies intense inflammatory response in the treatment of acne vulgaris via CXCL8. Exp Dermatol, 30(7): 923-931. [DOI:10.1111/exd.14357] [PMID]
22. Kim HK, Yeo IK, Li K, et al. (2014) Topical epidermal growth factor for the improvement of acne lesions: a randomized double-blinded placebo-controlled split-face trial Int J Dermatol, 53(8): 1031-1036. [DOI:10.1111/ijd.12488] [PMID]
23. Chayahara N, Mukohara T, Tachihara M, et al. (2019) Adapalene gel 0,1% versus placebo as prophylaxis for anti-epidermal growth factor receptor-induced acne-like rash: A randomized left-right comparative evaluation (APPEARANCE) Oncologist, 24(7): 885-e413. [DOI:10.1634/theoncologist.2019-0156] [PMID] []
24. Torocsik D, Fazekas F, Poliska S, et al. (2021) Epidermal growth factor modulates palmitic acid-induced inflammatory and lipid signaling pathways in SZ95 sebocytes. Front Immunol, 12: 600017. [DOI:10.3389/fimmu.2021.600017] [PMID] []
25. Kim JM, Choo JE, Lee HJ, et al. (2018) Epidermal growth factor attenuated the expression of inflammatory cytokines in human epidermal keratinocyte exposed to propionibacterium acnes. Ann Dermatol, 30(1):54-63. [DOI:10.5021/ad.2018.30.1.54] [PMID] []
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Liao L, Lu F. Effect of ultrasound-guided epidermal growth factor injection combined with carbon dioxide laser on treatment of facial acne scars. Int J Radiat Res 2023; 21 (4) :713-717
URL: http://ijrr.com/article-1-5065-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 21, Issue 4 (10-2023) Back to browse issues page
International Journal of Radiation Research
Persian site map - English site map - Created in 0.05 seconds with 50 queries by YEKTAWEB 4714