Evaluation of clinical efficacy of ultrasound-guided joint injection of hypertonic glucose combined with blood flow restriction training in the treatment of rotator cuff injury

Gu, F.; Deng, M.; Zhao, Y.; Chen, X.; An, L.; Zhao, Z.

doi:10.61882/ijrr.23.3.20

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Volume 23, Issue 3 (7-2025) Int J Radiat Res 2025, 23(3): 651-658 | Back to browse issues page

‎ 10.61882/ijrr.23.3.20

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Gu F, Deng M, Zhao Y, Chen X, An L, Zhao Z. Evaluation of clinical efficacy of ultrasound-guided joint injection of hypertonic glucose combined with blood flow restriction training in the treatment of rotator cuff injury. Int J Radiat Res 2025; 23 (3) :651-658
URL: http://ijrr.com/article-1-6610-en.html

Evaluation of clinical efficacy of ultrasound-guided joint injection of hypertonic glucose combined with blood flow restriction training in the treatment of rotator cuff injury

F. Gu

, M. Deng

, Y. Zhao

, X. Chen

, L. An

, Z. Zhao

Avic Xi’an Aircraft Industry Group Company Ltd, No.1 Xifei Avenue, Yanliang District, Xi’an, Shaanxi Province, China , zhao900803zhen@hotmail.com

Abstract: (354 Views)

Background: Rotator cuff injuries are common musculoskeletal conditions that impair shoulder function and quality of life. Conventional therapies often fail to address the biological and mechanical deficiencies of these injuries. This study evaluated the clinical efficacy of ultrasound-guided hypertonic glucose injections combined with blood flow restriction (BFR) training in managing rotator cuff injuries. Materials and Methods: A randomized controlled trial involving 120 patients with rotator cuff injuries was conducted. Participants were assigned to an experimental group (ultrasound-guided glucose injections with BFR training, n=60) or a control group (standard physical therapy, n=60). Pain, shoulder function, tendon thickness, range of motion (ROM), muscle strength, and patient-reported outcomes were assessed over 12 weeks using ultrasound imaging and validated scales (visual analog scale (VAS), Constant–Murley score (CMS), shoulder disability index (SDI), and American Shoulder and Elbow Surgeons (ASES) score). Results: The experimental group showed significant improvements compared to the control group, including reduced pain (VAS: -3.0, p<0.001), enhanced function (CMS: +29.5, p<0.001), increased ROM (+25°, p<0.001), decreased tendon thickness (-1.7 mm, p<0.001), and improved muscle strength (+2.8 kg, p<0.001). Patient-reported satisfaction and functionality (ASES: +33.4, p<0.001) were also higher in the experimental group. Conclusion: The combination of hypertonic glucose injections and BFR training is an effective approach for treating rotator cuff injuries. It provides significant pain relief, functional recovery, and structural improvements, which highlight its potential as a better alternative to conventional treatments. Further research is recommended to assess the long-term efficacy and refine the treatment protocols.

Keywords: Rotator Cuff Injuries, hypertonic glucose, blood flow restriction training, ultrasound-guided, musculoskeletal rehabilitation.

Full-Text [PDF 781 kb] (89 Downloads)

Type of Study: Original Research | Subject: Radiation Biology

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